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Flights from Des Moines to Charlotte from $76

Explore flight options from Des Moines to Charlotte with competitive pricing starting from $377.
Des Moines

DSM

→

Charlotte

CLT

11/05/2025 – 11/12/2025

Cheap flight deals from Des Moines to Charlotte

Average price start from:
i

$110

Round-trip flights from Des Moines to Charlotte starting at $110. Book now for the best deals!

One-way from:
i

$76

One-way flights from Des Moines to Charlotte starting at $76. Great for flexible travel!

Cheapest day:
i

Thursday

Thursday is the cheapest day to fly from Des Moines to Charlotte. Save more by booking on this day!

Cheapest In:
i

$134

May 2025

May 2025 is the cheapest month to fly from Des Moines to Charlotte with prices starting at $134.

Find flight deals from Des Moines to Charlotte

Cheapest flights from Des Moines to Charlotte

ONEWAY FLIGHTS

LAST MINUTE

CHEAP FLIGHTS

BEST FLIGHTS

Explore the cheapest oneway flights from Des Moines to Charlotte spotted daily.

DSM

Des Moines

DSM - Des Moines • 2025-11-05 • 09:00

Unknown

60 min

CLT

Unknown City

$76

Non-stop • 60 min

OMA

Des Moines

OMA - Des Moines • 2025-11-05 • 09:00

Unknown

60 min

CLT

Unknown City

$81

Non-stop • 60 min

CID

Des Moines

CID - Des Moines • 2025-11-05 • 09:00

Unknown

60 min

RDU

Unknown City

$100

Non-stop • 60 min

CID

Des Moines

CID - Des Moines • 2025-11-05 • 09:00

Unknown

60 min

RDU

Unknown City

$129

Non-stop • 60 min

CID

Des Moines

CID - Des Moines • 2025-11-05 • 09:00

Unknown

60 min

CLT

Unknown City

$147

Non-stop • 60 min

DSM

Des Moines

DSM - Des Moines • 2025-11-05 • 09:00

Unknown

60 min

RDU

Unknown City

$149

Non-stop • 60 min

DSM

Des Moines

DSM - Des Moines • 2025-11-05 • 09:00

Unknown

60 min

RDU

Unknown City

$154

Non-stop • 60 min

OMA

Des Moines

OMA - Des Moines • 2025-11-05 • 09:00

Unknown

60 min

MYR

Unknown City

$159

Non-stop • 60 min

OMA

Des Moines

OMA - Des Moines • 2025-11-05 • 09:00

Unknown

60 min

CLT

Unknown City

$163

Non-stop • 60 min

DSM

Des Moines

DSM - Des Moines • 2025-11-05 • 09:00

Unknown

60 min

CLT

Unknown City

$163

Non-stop • 60 min

OMA

Des Moines

OMA - Des Moines • 2025-11-05 • 09:00

Unknown

60 min

CLT

Unknown City

$173

Non-stop • 60 min

DSM

Des Moines

DSM - Des Moines • 2025-11-05 • 09:00

Unknown

60 min

CLT

Unknown City

$173

Non-stop • 60 min

Price Trends & Analysis

Weekly Price Trends

Optimal pricing available on Thursday for flights to Charlotte.

Monthly Price Trends

Lowest fares from Des Moines to Charlotte typically available in April.

Weather & Climate Information

Temperature

Charlotte experiences a humid subtropical climate with summer temperatures averaging 80°F to 90°F (27°C to 32°C) and winter temperatures ranging from 30°F to 50°F (-1°C to 10°C). The best times for comfortable travel are spring (March to May) and fall (September to November), when temperatures are mild and rainfall is moderate.

Rainfall

The best time to visit Charlotte is during the spring (March to May) when temperatures are mild and flowers bloom, creating a pleasant atmosphere. Additionally, plan your trip around local events like the Charlotte Jazz Festival in April or the NASCAR All-Star Race in May for a vibrant experience.

Airlines at Charlotte

Experience seamless travel from Des Moines to Charlotte with trusted airlines like Frontier Airlines, American Airlines, Delta Air Lines, United Airlines. These carriers ensure reliable connections and flexible scheduling options for travelers. Flight duration typically ranges around 10-15 hours, with most routes including one stopover in major aviation hubs. For your trip from Des Moines to Charlotte, these airlines offer modern amenities and professional service to make your journey comfortable and enjoyable.

Places to Visit in Charlotte

Nestled in the heart of the Carolinas, Charlotte dazzles with its vibrant skyline and rich blend of Southern charm and modern innovation. Visitors can explore the historic Fourth Ward, where Victorian homes whisper stories of the past, or immerse themselves in the excitement of the NASCAR Hall of Fame. With a thriving arts scene, tantalizing culinary offerings, and lush parks, Charlotte invites travelers to experience a dynamic city that celebrates both its heritage and its forward-thinking spirit.

About Charlotte

Discover the beauty of Charlotte when flying from Des Moines. This captivating city combines rich heritage with contemporary charm, offering something special for every traveler. Plan your visit during off-peak periods for optimal savings and a more relaxed experience.

Airlines Flying from Des Moines to Charlotte

Experience seamless travel from Des Moines to Charlotte with trusted airlines like Frontier Airlines, American Airlines, Delta Air Lines, United Airlines. These carriers ensure reliable connections and flexible scheduling options for travelers. Flight duration typically ranges around 10-15 hours, with most routes including one stopover in major aviation hubs. For your trip from Des Moines to Charlotte, these airlines offer modern amenities and professional service to make your journey comfortable and enjoyable.

Hotels in Charlotte

For convenient stays near Charlotte, consider these hotels close to CLT Airport. These properties ensure easy access to CLT Airport while offering comfortable accommodations. Many provide complimentary shuttle services for seamless airport transfers.
Hotel

Hotel

Category: Standard

Comfortable accommodations with modern amenities.

Location: Near airport

Hotel ID:

About Charlotte

Discover the beauty of Charlotte when flying from Des Moines. This captivating city combines rich heritage with contemporary charm, offering something special for every traveler. Plan your visit during off-peak periods for optimal savings and a more relaxed experience.

Places to Visit in Charlotte

Nestled in the heart of the Carolinas, Charlotte dazzles with its vibrant skyline and rich blend of Southern charm and modern innovation. Visitors can explore the historic Fourth Ward, where Victorian homes whisper stories of the past, or immerse themselves in the excitement of the NASCAR Hall of Fame. With a thriving arts scene, tantalizing culinary offerings, and lush parks, Charlotte invites travelers to experience a dynamic city that celebrates both its heritage and its forward-thinking spirit.

Hotels in Charlotte

For convenient stays near Charlotte, consider these hotels close to CLT Airport. These properties ensure easy access to CLT Airport while offering comfortable accommodations. Many provide complimentary shuttle services for seamless airport transfers.
Hotel

Hotel

Category: Standard

Comfortable accommodations with modern amenities.

Location: Near airport

Hotel ID:

Airlines Flying from Des Moines to Charlotte

Experience seamless travel from Des Moines to Charlotte with trusted airlines like Frontier Airlines, American Airlines, Delta Air Lines, United Airlines. These carriers ensure reliable connections and flexible scheduling options for travelers. Flight duration typically ranges around 10-15 hours, with most routes including one stopover in major aviation hubs. For your trip from Des Moines to Charlotte, these airlines offer modern amenities and professional service to make your journey comfortable and enjoyable.

Frequently Asked Questions

What's the best deal for flights from Des Moines to Charlotte?

The lowest fare available is $76. Maximize savings by booking during April and selecting Thursday flights.

How many hours does it take to fly from Des Moines to Charlotte?

Flight duration typically ranges around 10-15 hours, with most flights including one stopover for optimal route efficiency.

Which carriers fly between Des Moines and Charlotte?

Major airlines serving this route include Frontier Airlines, American Airlines, Delta Air Lines. Each offers different schedules and amenities to suit various travel preferences.

What's the ideal booking window for this route?

Book 2-3 months in advance for the best prices. Traveling during April can provide additional savings opportunities.

Are there convenient hotels near CLT Airport?

Yes, CLT Airport is surrounded by hotels offering shuttle services and modern amenities for travelers.

Why should I visit Charlotte?

Charlotte offers an incredible mix of cultural experiences and modern attractions. Plan your visit during pleasant weather months for the most enjoyable experience.

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