Explore flight options from Des Moines to Phoenix with competitive pricing starting from $262.
Des Moines
DSM
→
Phoenix
AZA
11/05/2025 – 11/12/2025
Cheap flight deals from Des Moines to Phoenix
Average price start from:
i
$219
Round-trip flights from Des Moines to Phoenix starting at $219. Book now for the best deals!
One-way from:
i
$61
One-way flights from Des Moines to Phoenix starting at $61. Great for flexible travel!
Cheapest day:
i
Thursday
Thursday is the cheapest day to fly from Des Moines to Phoenix. Save more by booking on this day!
Cheapest In:
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$105
Jul 2025
Jul 2025 is the cheapest month to fly from Des Moines to Phoenix with prices starting at $105.
Find flight deals from Des Moines to Phoenix
Cheapest flights from Des Moines to Phoenix
ONEWAY FLIGHTS
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Explore the cheapest oneway flights from Des Moines to Phoenix spotted daily.
DSM
Des Moines
DSM - Des Moines • 2025-11-05 • 09:00
Unknown
60 min
AZA
Unknown City
$61
Non-stop • 60 min
DSM
Des Moines
DSM - Des Moines • 2025-11-05 • 09:00
Unknown
60 min
AZA
Unknown City
$271
Non-stop • 60 min
Price Trends & Analysis
Weekly Price Trends
Save money by choosing Thursday flights to Phoenix.
Monthly Price Trends
The cheapest month for flights from Des Moines to Phoenix is September.
Weather & Climate Information
Temperature
Mesa has a desert climate with hot summers (average highs above 38°C/100°F from June to September), mild winters (average highs around 20°C/68°F), and low annual rainfall. Expect abundant sunshine year-round.[3][4]
Rainfall
The best time to visit Mesa is from late October to April, when temperatures are comfortable for outdoor activities and festivals are frequent.
Airlines at AZA
Discover excellent flight options from Des Moines to Phoenix with top airlines including Allegiant Air. These carriers offer reliable service and comfortable connections between these popular destinations.
The average flight time is approximately 10-15 hours, with most routes featuring one stopover for optimal pricing and convenience. When planning your journey from Des Moines to Phoenix, these airlines provide excellent connectivity and modern aircraft for a pleasant travel experience.
Places to Visit in Phoenix
Top places to visit in Mesa include the **Mesa Arts Center**, Arizona’s largest arts complex, featuring theaters, galleries, and art studios with year-round performances and exhibitions.; the **Arizona Museum of Natural History**, Premier natural history museum with dinosaur exhibits, archaeological artifacts, and interactive displays.; the **Commemorative Air Force Airbase Arizona Museum**, Military aviation museum with vintage aircraft and flight experiences.; the **Usery Mountain Regional Park**, Scenic park offering hiking, biking, and panoramic desert views.; and the **Mesa Arizona Temple Visitors' Center**, Modern visitors' center adjacent to the historic Mesa Arizona Temple, featuring interactive exhibits..
About Phoenix
Embark on an incredible journey from Des Moines to Phoenix and immerse yourself in the charm of this remarkable destination. Mesa is Arizona's third-largest city, known for its vibrant arts scene, rich Native American heritage, and proximity to the Sonoran Desert. The city offers a blend of cultural attractions, outdoor adventures, and family-friendly activities, making it a diverse destination for travelers.[3][4]
Mesa's history dates back to the Hohokam people, who built extensive canal systems in the region. The city later became a settlement for Mormon pioneers in the late 19th century and has since grown into a major urban center with a strong aviation and agricultural legacy.[4][5]
For optimal weather conditions, visit Phoenix during Peak season is from January to March, coinciding with MLB Spring Training and cooler weather, attracting sports fans and tourists. when outdoor activities are at their best.
Save significantly on your trip by booking flights from Des Moines to Phoenix in September and selecting Thursday flights. Experience the local way of life and taste the authentic flavors of Phoenix.
Airlines Flying from Des Moines to Phoenix
Discover excellent flight options from Des Moines to Phoenix with top airlines including Allegiant Air. These carriers offer reliable service and comfortable connections between these popular destinations.
The average flight time is approximately 10-15 hours, with most routes featuring one stopover for optimal pricing and convenience. When planning your journey from Des Moines to Phoenix, these airlines provide excellent connectivity and modern aircraft for a pleasant travel experience.
Hotels in Phoenix
For your visit to Phoenix, choose hotels near AZA Airport for maximum convenience. Many accommodations offer complimentary airport shuttle services.
Airport Statistics
As a premier transportation hub, the airport boasts extensive connectivity with both domestic and international flight routes, facilitating seamless travel through advanced air traffic management systems. Equipped with state-of-the-art facilities, including efficient check-in counters, passenger lounges, and automated baggage handling, the airport ensures an exceptional travel experience with comprehensive services tailored to meet the diverse needs of modern travelers.
About Phoenix
Embark on an incredible journey from Des Moines to Phoenix and immerse yourself in the charm of this remarkable destination. Mesa is Arizona's third-largest city, known for its vibrant arts scene, rich Native American heritage, and proximity to the Sonoran Desert. The city offers a blend of cultural attractions, outdoor adventures, and family-friendly activities, making it a diverse destination for travelers.[3][4]
Mesa's history dates back to the Hohokam people, who built extensive canal systems in the region. The city later became a settlement for Mormon pioneers in the late 19th century and has since grown into a major urban center with a strong aviation and agricultural legacy.[4][5]
For optimal weather conditions, visit Phoenix during Peak season is from January to March, coinciding with MLB Spring Training and cooler weather, attracting sports fans and tourists. when outdoor activities are at their best.
Save significantly on your trip by booking flights from Des Moines to Phoenix in September and selecting Thursday flights. Experience the local way of life and taste the authentic flavors of Phoenix.
Places to Visit in Phoenix
Top places to visit in Mesa include the **Mesa Arts Center**, Arizona’s largest arts complex, featuring theaters, galleries, and art studios with year-round performances and exhibitions.; the **Arizona Museum of Natural History**, Premier natural history museum with dinosaur exhibits, archaeological artifacts, and interactive displays.; the **Commemorative Air Force Airbase Arizona Museum**, Military aviation museum with vintage aircraft and flight experiences.; the **Usery Mountain Regional Park**, Scenic park offering hiking, biking, and panoramic desert views.; and the **Mesa Arizona Temple Visitors' Center**, Modern visitors' center adjacent to the historic Mesa Arizona Temple, featuring interactive exhibits..
Hotels in Phoenix
For your visit to Phoenix, choose hotels near AZA Airport for maximum convenience. Many accommodations offer complimentary airport shuttle services.
Airlines Flying from Des Moines to Phoenix
Discover excellent flight options from Des Moines to Phoenix with top airlines including Allegiant Air. These carriers offer reliable service and comfortable connections between these popular destinations.
The average flight time is approximately 10-15 hours, with most routes featuring one stopover for optimal pricing and convenience. When planning your journey from Des Moines to Phoenix, these airlines provide excellent connectivity and modern aircraft for a pleasant travel experience.
Frequently Asked Questions
What is the cheapest flight from Des Moines to Phoenix?
The cheapest fare is $61. For the best deals, consider booking during September and flying on Thursday.
How long is the flight from Des Moines to Phoenix?
Average flight time is around 10-15 hours, depending on layovers and the chosen route. Most flights include one stopover for optimal pricing.
Which airlines fly from Des Moines to Phoenix?
Multiple airlines operate this route including Allegiant Air. Check current schedules and availability for the best options.
What is the best time to book flights?
Booking 2–3 months in advance usually gives the best prices. Consider flying during September for additional savings.
Are there hotels near AZA Airport?
Yes, several hotels are conveniently located near AZA Airport, including options with shuttle services for easy airport access.
What should I know about Phoenix?
Phoenix offers a perfect blend of culture, history, and modern attractions. The best time to visit is during Peak season is from January to March, coinciding with MLB Spring Training and cooler weather, attracting sports fans and tourists. for optimal experiences.
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