Book your flight from Cartagena (CTG) to Medellín (MDE) at the best prices. Fares start from $55.
Cartagena
CTG
→
Medellín
MDE
10/24/2025 – 10/31/2025
Cheap flight deals from Cartagena to Medellín
Average price start from:
i
$43
Round-trip flights from Cartagena to Medellín starting at $43. Book now for the best deals!
One-way from:
i
$21
One-way flights from Cartagena to Medellín starting at $21. Great for flexible travel!
Cheapest day:
i
Thursday
Thursday is the cheapest day to fly from Cartagena to Medellín. Save more by booking on this day!
Cheapest In:
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$8
Apr 2025
Apr 2025 is the cheapest month to fly from Cartagena to Medellín with prices starting at $8.
Find flight deals from Cartagena to Medellín
Cheapest flights from Cartagena to Medellín
ONEWAY FLIGHTS
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Explore the cheapest oneway flights from Cartagena to Medellín spotted daily.
CTG
Cartagena
CTG - Cartagena • 2025-10-24 • 09:00
Unknown
60 min
MDE
Unknown City
$21
Non-stop • 60 min
CTG
Cartagena
CTG - Cartagena • 2025-10-24 • 09:00
Unknown
60 min
MDE
Unknown City
$23
Non-stop • 60 min
CTG
Cartagena
CTG - Cartagena • 2025-10-24 • 09:00
Unknown
60 min
MDE
Unknown City
$27
Non-stop • 60 min
CTG
Cartagena
CTG - Cartagena • 2025-10-24 • 09:00
Unknown
60 min
MDE
Unknown City
$57
Non-stop • 60 min
CTG
Cartagena
CTG - Cartagena • 2025-10-24 • 09:00
Unknown
60 min
MDE
Unknown City
$70
Non-stop • 60 min
CTG
Cartagena
CTG - Cartagena • 2025-10-24 • 09:00
Unknown
60 min
MDE
Unknown City
$982
Non-stop • 60 min
Price Trends & Analysis
Weekly Price Trends
If your flying dates are flexible, consider flying to Medellín on a Thursday.
Monthly Price Trends
Lowest fares from Cartagena to Medellín typically available in April.
Weather & Climate Information
Temperature
Rionegro has a subtropical highland climate, with mild temperatures year-round. Average daytime temperatures range from 17°C to 22°C (63°F to 72°F), with frequent rainfall, especially from April to November. Nights can be cool due to the city's elevation of over 2,100 meters (6,900 ft) above sea level.
Rainfall
The best time to visit Rionegro is during the dry season, from December to March, when rainfall is minimal and outdoor activities are more enjoyable.
Airlines at MDE
Book your journey from Cartagena to Medellín with leading airlines including JetSMART, wingo, Avianca, LATAM Airlines Chile. These carriers provide excellent connectivity and multiple daily options for convenient travel.
The typical flight time is about 10-15 hours, with most flights featuring one stopover for better pricing and route optimization. When traveling from Cartagena to Medellín, these airlines ensure a smooth and comfortable experience with their modern fleet and professional service.
Places to Visit in Medellín
Top places to visit in Rionegro include the **Parque Principal de Rionegro**, The main square of Rionegro, surrounded by colonial architecture, cafes, and the historic Catedral de San Nicolás.; the **Catedral de San Nicolás**, A historic cathedral located in the heart of Rionegro, known for its neoclassical architecture and cultural significance.; the **Museo Histórico Casa de la Convención**, A museum housed in a colonial building where the 1863 Rionegro Constitution was signed, showcasing local history.; and the **Comfama Rionegro Park**, A large recreational park offering sports facilities, swimming pools, and family activities..
About Medellín
Embark on an incredible journey from Cartagena to Medellín and immerse yourself in the charm of this remarkable destination. Rionegro is a city in the Antioquia Department of Colombia, known for its proximity to Medellín and as the location of José María Córdova International Airport (MDE), the main international gateway for the Medellín metropolitan area. The city is surrounded by lush green hills and is a hub for both business and tourism in the region.[2][1]
Rionegro has colonial roots and played a significant role in Colombia's independence movement. The José María Córdova International Airport, named after a local independence hero, opened in 1985 and has since become the second largest airport in Colombia, serving as a major hub for both domestic and international travel.[1][2]
For optimal weather conditions, visit Medellín during Peak travel season is December to January and during major Colombian holidays, when both tourism and flight traffic increase significantly. when outdoor activities are at their best.
Save significantly on your trip by booking flights from Cartagena to Medellín in April and selecting Thursday flights. Experience the local way of life and taste the authentic flavors of Medellín.
Airlines Flying from Cartagena to Medellín
Book your journey from Cartagena to Medellín with leading airlines including JetSMART, wingo, Avianca, LATAM Airlines Chile. These carriers provide excellent connectivity and multiple daily options for convenient travel.
The typical flight time is about 10-15 hours, with most flights featuring one stopover for better pricing and route optimization. When traveling from Cartagena to Medellín, these airlines ensure a smooth and comfortable experience with their modern fleet and professional service.
Hotels in Medellín
For your visit to Medellín, choose hotels near MDE Airport for maximum convenience. Many accommodations offer complimentary airport shuttle services.
Airport Statistics
As a premier transportation hub, the airport boasts extensive connectivity with multiple domestic and international flight routes, facilitating seamless passenger transfers through its efficient terminal design. Equipped with state-of-the-art facilities, including automated check-in kiosks, lounges, and diverse dining options, the airport ensures a superior travel experience, catering to the needs of both leisure and business travelers.
About Medellín
Embark on an incredible journey from Cartagena to Medellín and immerse yourself in the charm of this remarkable destination. Rionegro is a city in the Antioquia Department of Colombia, known for its proximity to Medellín and as the location of José María Córdova International Airport (MDE), the main international gateway for the Medellín metropolitan area. The city is surrounded by lush green hills and is a hub for both business and tourism in the region.[2][1]
Rionegro has colonial roots and played a significant role in Colombia's independence movement. The José María Córdova International Airport, named after a local independence hero, opened in 1985 and has since become the second largest airport in Colombia, serving as a major hub for both domestic and international travel.[1][2]
For optimal weather conditions, visit Medellín during Peak travel season is December to January and during major Colombian holidays, when both tourism and flight traffic increase significantly. when outdoor activities are at their best.
Save significantly on your trip by booking flights from Cartagena to Medellín in April and selecting Thursday flights. Experience the local way of life and taste the authentic flavors of Medellín.
Places to Visit in Medellín
Top places to visit in Rionegro include the **Parque Principal de Rionegro**, The main square of Rionegro, surrounded by colonial architecture, cafes, and the historic Catedral de San Nicolás.; the **Catedral de San Nicolás**, A historic cathedral located in the heart of Rionegro, known for its neoclassical architecture and cultural significance.; the **Museo Histórico Casa de la Convención**, A museum housed in a colonial building where the 1863 Rionegro Constitution was signed, showcasing local history.; and the **Comfama Rionegro Park**, A large recreational park offering sports facilities, swimming pools, and family activities..
Hotels in Medellín
For your visit to Medellín, choose hotels near MDE Airport for maximum convenience. Many accommodations offer complimentary airport shuttle services.
Airlines Flying from Cartagena to Medellín
Book your journey from Cartagena to Medellín with leading airlines including JetSMART, wingo, Avianca, LATAM Airlines Chile. These carriers provide excellent connectivity and multiple daily options for convenient travel.
The typical flight time is about 10-15 hours, with most flights featuring one stopover for better pricing and route optimization. When traveling from Cartagena to Medellín, these airlines ensure a smooth and comfortable experience with their modern fleet and professional service.
Frequently Asked Questions
What's the lowest price for flights from Cartagena to Medellín?
You can find flights starting from $21. For better deals, book during April and choose Thursday departures.
How long is the journey from Cartagena to Medellín?
The average flight time is about 10-15 hours, with most routes including one stopover for better pricing and comfort.
What airlines operate flights on this route?
Several airlines serve this route including JetSMART, wingo, Avianca. Research current schedules and compare prices for the best deal.
How far in advance should I book?
For the best prices, book 2-3 months ahead and consider traveling during April when prices are typically lower.
What accommodation options are near MDE Airport?
MDE Airport has several nearby hotels with shuttle services, making it convenient for travelers with early or late flights.
What attractions can I visit in Medellín?
Medellín features a wonderful combination of historical sites and modern attractions. The best time to visit is during Peak travel season is December to January and during major Colombian holidays, when both tourism and flight traffic increase significantly. for optimal sightseeing.
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